VCF MCP Server

Example Use Cases

• 1

  Query genomic variants at specific positions.

• 2

  Retrieve variants within a genomic region.

• 3

  Look up variants by their variant ID.

Description

This server allows querying of genomic variants from a single VCF file using large language models (LLMs). It supports queries by genomic position, region, or variant ID, facilitating efficient variant analysis in desktop or confidential compute environments. The server works best with compressed VCF files indexed by tabix for optimal performance and supports both stdio and HTTP/SSE transports.