Liftover MCP Server

Example Use Cases

• 1

  Convert single genomic positions from one assembly to another using the Broad Institute's liftover service.

• 2

  Lift over genomic intervals, variants (with ref/alt), or HGVS-formatted coordinates programmatically within MCP workflows.

• 3

  Integrate liftover functionality into automated pipelines or tools that orchestrate genomic data transformations.

Description

This MCP server wraps the Broad Institute's Liftover tool to offer programmatic access for converting genomic coordinates between genome builds. It supports single positions, intervals, variant conversions (with ref/alt), and HGVS notations, and is designed to integrate with MCP/fastmcp workflows. The tool is intended to automate liftover operations in pipelines and agent-driven processes while relying on the Broad Institute's liftover service for conversion functionality.